药食植物鱼腥草对亚硝化反应抑制作用的研究_陈达畅

目前，癌症已成为威胁人类生命的最大杀手，亚硝酸盐与胺类化合物在酸性环境下或细菌作用下容易形成N-亚硝基化合物（NC），NC有强烈的致癌性。研究表明，在米面饼中加入少量的亚硝酸盐可形成大量NC[1]。研究还发现，许多新鲜水果、蔬菜及天然植物药材如葱、蒜、金钱兰、刘寄奴等[2-5]有较强清除亚硝酸盐的能力，即有较好的防癌作用[1-2]。鱼腥草，性寒味微苦，具有清热解毒、消肿排脓、利尿通淋的功效。主要StudyonInhibitionofNitrosationbyExtractsofFoodandMedicinePlantHouttuyniacordataThunb.CHENDa-chang1，CHENLi-li1，XUGuo-quan2（1.WuhanForeignLanguagesSchool,Wuhan430022,China;2.SchoolofLifeScience,JianghanUniversity,Wuhan430056,China）Abstract：ThispaperstudiedthecontentoftotalflavonoidsandtotalphenolsinHouttuyniacordataThunb.activesubstanceextractedbyfivedifferentsolvents,whenthesolid-to-liquidrationwas1∶10,extractiontemperaturewas80℃,extractiontimewas60minutes.AndtheirblockingeffectsontheformationofNDMAandscavengingeffectsonsodiumnitritewerestudied.Theresultsshowedthat,thecontentsoftotalflavonoidsandtotalphenolsinHouttuyniacordataThunb.activesubstancewasthehighestwhichextractedby55%acetone,andwiththeoptimumconcentrationofacetone,theblockingrateofNDMAofHouttuyniacordataThunb.activesubstancecould