水溶性-环糊精聚合物和疏水改性聚丙烯酰胺的主客体相互作用

2005年第63卷化学学报Vol.63,2005第19期,1841～1846ACTACHIMICASINICANo.19,1841～1846*E-mail:fpwu@mail.ipc.ac.cnReceivedJanuary10,2005;revisedMay30,2005;acceptedJuly4,2005.·研究论文·水溶性β-环糊精聚合物和疏水改性聚丙烯酰胺的主客体相互作用李姝静a吴飞鹏*,a李妙贞a王尔鑑a毛诗珍b杜有如b(a中国科学院理化技术研究所北京100101)(b中国科学院武汉物理与数学研究所波谱与原子分子物理国家重点实验室武汉430071)摘要摘要主体环糊精聚合物(β-CDE)与客体疏水改性丙烯酰胺共聚物P(AM/POEA)构成超分子结构的高分子识别体系.这种客体聚合物是含有少量疏水体(xPOEA＜0.01)的水溶性聚合物,NMR测定结果表明β-CDE和P(AM/POEA)的主客体相互作用是通过环糊精空腔和疏水体POEA形成包结络合物进行的.在P(AM/POEA)聚合物水溶液中加入β-CDE,由于主客体聚合物相互作用出现粘度的大幅上升,增粘的幅度可通过改变聚合物浓度和疏水体含量来调节,同时对盐浓度和温度的影响也进行了研究.通过透射电镜直观观察的结果表明,此类缔合聚合物体系的主客体相互作用生成实心球状多分子聚集体.关键词关键词包结缔合物;主客体相互作用;β-环糊精聚合物;疏水改性聚丙烯酰胺;多分子聚集体Host-guestInteractionbetweenWater-solubleβ-CyclodextrinPolymerandHydrophobicallyModifiedPolyacrylamideLI,Shu-JingaWU,Fei-Peng*,aLI,Miao-ZhenaWANG,Er-JianaMAO,Shi-ZhenbDU,You-Rub(aTechnicalInstituteofPhysicsandChemistry,ChineseAcademyofSciences,Beijing100101)(bStateKeyLaboratoryofMagneticandAtomicandMolecularPhysics,WuhanInstituteofPhysicsandMathematics,ChineseAcademyofSciences,Wuhan430071)AbstractAsupramolecularrecognizingsystemwasconstructedbasedonthewater-solubleβ-cyclodextrinpolymer(β-CDE)ashostandhydrophobicallymodifiedpolyacrylamideP(AM/POEA)asguest.Suchguestpolymerisawatersolublepolymercontainingasmallamountofhydrophobe(xPOEA＜0.01).TheresultsofNMRmeasurementindicatedthatthehost-guestinteractionbetweenβ-CDEandP(AM/POEA)wascarriedoutthroughtheformationofinclusioncomplexesbetweencyclodextrincavityandthehydrophobePOEA.Highviscosityenhancementswereobservedwhenβ-CDEwasaddedtoP(AM/POEA)solutionsasaresultofthepolymerinclusionassociation,whichcanbecontrolledbyvaryingthepolymerconcentrationandhy-drophobecontent.Theinfluencesofsaltconcentrationandtemperatureontheviscosityofmixturesolutionwerealsostudied.TheTEMimagesdemonstratedthatthehost-guestinteractionbetweenβ-CDEandP(AM/POEA)ledtotheformationofmulti-polymericaggregatewithsolidspherestructure.Keywordsinclusioncomplex;host-guestinteraction;β-cyclodextrinpolymer;hydrophobicallymodifiedpolyacrylamide;multimolecul