PM2.5对人体健康影响的英文文献

Short-termeffectoffineparticulatematter(PM2.5)ondailymortalityduetodiseasesofthecirculatorysysteminMadrid(Spain)T.Matéa,R.Guaitab,M.Pichiulec,C.Linaresd,J.Díaze,⁎aDepartmentofPreventiveMedicine,ClinicalUniversityTeachingHospital,Valladolid,SpainbDepartmentofPreventiveMedicine,DoctorPesetUniversityTeachingHospital,Valencia,SpaincDepartmentofPreventiveMedicine,LaPrincesaUniversityTeachingHospital,Madrid,SpaindNationalCentreforEpidemiology,EnvironmentalEpidemiologyandCancerUnit,CarlosIIIInstituteofHealth,SpaineNationalSchoolofPublicHealth,CarlosIIIInstituteofHealth,Madrid,SpainabstractarticleinfoArticlehistory:Received14April2010Receivedinrevisedform27July2010Accepted30July2010Availableonline9September2010Keywords:PM2.5FineparticulatematterAirpollutionMortalityCardiovasculardiseasesIntroduction:Owingtotheirsmallsize,fineparticles,i.e.,thosehavingadiameter≤2.5μm(PM2.5),haveahighalveolarpenetrationcapacity,therebytriggeringalocalinflammatoryprocesswithcirculatoryrepercussion.Despitebeinglinkedtorespiratoryandcardiovascularmorbidities,thereislimitedevidenceofanassociationbetweenthistypeofparticulatematterandshort-termincreasesinmortality.Objective:Theaimofthisstudywastoanalyseandquantifytheshort-termimpactofPM2.5ondailymortalityduetodiseasesofthecirculatorysystem,registeredinMadridfrom1January2003to31December2005.Methods:Anecologicallongitudinaltime-seriesstudywasconducted,withrisksbeingquantifiedbymeansofPoissonregressionmodels.Asadependentvariable,wetookdailymortalityregisteredinMadridfrom1January2003to31December2005,attributedtoalldiseasesofthecirculatorysystemasclassifiedunderheadsI00–I99oftheInternationalClassificationofDiseases-10threvision(ICD-10)andbrokendownasfollows:I21,acutemyocardialinfarction(AMI);I20,I22–I25,otherischemicheartdiseases;andI60–I69,cerebrovasculardiseases.TheindependentvariablewasdailymeanPM2.5concentration.Theothervariablescontrolledforwere:chemicalpollution(PM10,O3,SO2,NO2andNOx);acousticandbioticpollution;influenza;minimumandmaximumtemperatu