速溶型二氧化氯泡腾片的杀菌效果试验及现场应用_王奎涛

第30卷第1期河北科技大学学报Vol.30,No.12009年3月JournalofHebeiUniversityofScienceandTechnologyMar.2009文章编号:1008-1542(2009)01-0045-06速溶型二氧化氯泡腾片的杀菌效果试验及现场应用王奎涛1,陈宏槟2,冀维锋3,刘燕1,贾翠玉2(1.河北科技大学化学与制药工程学院,河北石家庄050018;2.华北制药集团北元有限公司,河北石家庄050015;3.河北省卫生厅卫生监督局,河北石家庄050071)摘要:介绍了速溶型二氧化氯泡腾片的杀菌效果,并对现场应用效果进行监测。将泡腾片分别制成50,100,150mg/L的二氧化氯消毒液,对5种常见微生物进行消毒实验,观察消毒效果。将泡腾片制成150mg/L的二氧化氯消毒液,应用于华北制药集团北元有限公司的制药洁净车间,对进入万级洁净区人员的手部、物料传递和万级区环境、设备进行消毒处理,监测现场应用效果。该速溶型二氧化氯泡腾片溶于水后,5min内即可完全溶解、活化;制成的150mg/L二氧化氯消毒液1min就可以杀灭全部受试微生物;活化后的二氧化氯消毒液存放时间超过1d,杀菌能力明显降低。实验得出速溶型二氧化氯泡腾片对细菌具有良好的杀灭效果,但使用时必须现用现配,制成的二氧化氯消毒液存放时间不得超过1d。关键词:二氧化氯;速溶型二氧化氯;泡腾片;微生物;消毒中图分类号:TQ635文献标识码:AStudyonthedisinfectioneffectofinstantchlorinedioxideeffervescetabletsanditsapplicationinspotWANGKui-tao1,CHENHong-bin2,JIWei-feng3,LIUYan1,JIACui-yu2(1.CollegeofChemicalandPharmaceuticalEngineering,HebeiUniversityofScienceandTechnology,ShijiazhuangHebei050018,China;2.BeiyuanCorporation,NorthChinaPharmaceuticalGroup,ShijiazhuangHebei050015,China;3.SupervisoryOfficeforSanitation,HebeiBureauofHealthSupervisory,ShijiazhuangHebei050071,China)Abstract:Tofindoutthedisinfecteffectofinstantchlorinedioxideeffervescetabletsandtomonitortheapplicationeffectinspot.Uses50,100,150mg/Lchlorinedioxidedisinfectionfluidtocarryonthedisinfectionexperimentseparatelytofivekindofcommonmicroorganisms,Theeffectwasobservedaftertheexperiment;uses150mg/Lchlorinedioxidedisinfectionfluidtothepeople'shandthatenterin10000cleanarea,materialtransfer,10000environmentalandequipmentdisinfectioninpharmaceuti-calsuncontaminatedworkshopsofBeiyuanCorporation.Theinstantchlorinedioxideeffervescetabletswasdissolvedandacti-vatedinwaterwithin5min;150mg/Lchlorinedioxidedisinfectionfluidcouldkillalltriedmicroorganismafteraffecting1min,italsohasthesameeffectonthepeople'shandthatenterin10000cleanarea,materialtransfer,10000environmentalandequipmentdisinfection,itseffectismostideal.Effervescetabletshavegoodsterilizingeffect,butitshouldbepreparedwhenusinganddonotkeepliquidemulsionfor1dafterprepared.Keywords:chlo