68 Trichoderma polysporum selectively inhibits whi

68 Trichoderma polysporum selectively inhibits white-nose syndrome fungal pathogen Pseudogymnoascus destructans amidst soil microbes.RESEARCHOpenAccessTrichodermapolysporumselectivelyinhibitswhite-nosesyndromefungalpathogenPseudogymnoascusdestructansamidstsoilmicrobesAmanpreetSingh1,EricaLasek-Nesselquist2,VishnuChaturvedi1,3andSudhaChaturvedi1,3*AbstractBackground:Pseudogymnoascusdestructans(Pd),thecausativefungalagentofwhite-nosesyndrome(WNS),hasledtothedeathsofmillionsofhibernatingbatsintheUnitedStatesofAmerica(USA)andCanada.EfficientstrategiesareneededtodecontaminatePdfromthebathibernaculatointerruptthediseasetransmissioncyclewithoutaffectingthenativemicrobes.Previously,wediscoveredanovelTrichodermapolysporum(Tp)strain(WPM39143),whichinhibitedthegrowthofPdinautoclavedsoilsamples.Inthepresentinvestigation,weusedculture-basedapproachestodetermineTp-inducedkillingofnativeandenrichedPdinthenaturalsoiloftwobathibernacula.WealsoassessedtheimpactofTptreatmentonnativemicrobialcommunitiesby